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CSRM617

CSRM617

Item no.	TMO-T10896-5mg
Manufacturer	TargetMol
CASRN	787504-88-5
Amount	5 mg
Quantity options	100 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	C(=NNC(C(CO)N)=O)C1=C(O)C(O)=C(O)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	255.23
Description	CSRM617 is a selective small molecule inhibitor of the transcription factor ONECUT2 (OC2, the main regulator of androgen receptor). The Kd in SPR analysis is 7.43 uM, which can directly bind to the OC2-HOX domain. CSRM617 induces apoptosis by cleaving the presence of Caspase-3 and PARP. CSRM617 is well tolerated in a mouse model of prostate cancer.
Pathways	Others

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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