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Elubrixin

Elubrixin

Item no.	TMO-T11179-10mg
Manufacturer	TargetMol
CASRN	688763-64-6
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C17H17Cl2FN4O4S
Smiles	S(=O)(=O)(C1=C(O)C(NC(NC2=C(Cl)C(F)=CC=C2)=O)=CC=C1Cl)N3CCNCC3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SB-656933
Shipping Condition	Cool pack
Available
Manufacturer - Targets	CXCR\|\|\|IL Receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	463.31
Description	Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin can be used for inflammatory diseases such as inflammatory bowel disease and airway inflammation. Elubrixin is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist.
Pathways	Immunology/Inflammation\|\|\|GPCR/G Protein\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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