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Nevanimibe hydrochloride

Nevanimibe hydrochloride

Item no.	TMO-T12225L-1mg
Manufacturer	TargetMol
CASRN	133825-81-7
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 200 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.25%
Citations	LaPensee CR, et al. ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs. Endocrinology. 2016 May;157(5):1775-88.
Smiles	Cl.CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(CCCC1)c1ccc(cc1)N(C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PD-132301 hydrochloride,ATR101 hydrochloride
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|Acyltransferase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	458.08
Description	Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active, selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) with an EC50 of 9 nM.
Pathways	Apoptosis\|\|\|Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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