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ON 146040

ON 146040

Item no.	TMO-T12310-5mg
Manufacturer	TargetMol
CASRN	1404231-34-0
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	CN1CCN(CC1)c1ccc(Nc2ncc3NC(=O)\C(Sc3n2)=C\c2ccc(cc2)[N+]([O-])=O)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ZINC211117138
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PI3K\|\|\|Bcr-Abl
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	489.55
Description	ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.
Pathways	Angiogenesis\|\|\|PI3K/Akt/mTOR signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cytoskeletal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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