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ADAMTS-5 Inhibitor

ADAMTS-5 Inhibitor

Item no.	TMO-T14124-200mg
Manufacturer	TargetMol
CASRN	929634-33-3
Amount	200 mg
Quantity options	100 mg 100 mg 1 mL x 10 mM (in DMSO) 1 mL x 10 mM (in DMSO) 10 mg 10 mg 1 mg 1 mg 1 mL 200 mg 200 mg 25 mg 25 mg 500 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	Cn1nc(c(\C=C2/SC(=S)NC2=O)c1SCc1ccc(Cl)cc1)C(F)(F)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	449, 92
Description	ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 µM and can be used in studies about cartilage destruction in arthritis.
Pathways	Others
Bioactivity	ADAMTS-5 Inhibitor is a potent ADAMTS-5 (aggrecanase-2) inhibitor, with an IC50 of 1.1 ÂµM. ADAMTS-5 Inhibitor shows >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1)[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 mg

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