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AKOS-22

AKOS-22

Item no.	TMO-T14150-25mg
Manufacturer	TargetMol
CASRN	878983-38-1
Amount	25 mg
Quantity options	100 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C22H21ClF3N3O3
Smiles	FC(F)(F)Oc1ccc(NC2CCN(CC2)C2CC(=O)N(C2=O)c2ccc(Cl)cc2)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Molecular Weight	467, 87
Pathways	Others
Bioactivity	AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 Î¼M). AKOS-22 protects against mitochondrial dysfunction[1]. AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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