Comparison

GNE-0723 European Partner

Item no. TMO-T15407-100mg
Manufacturer TargetMol
CASRN 1883518-31-7
Amount 100 mg
Quantity options 100 mg 10 mg 10 mg 1 mg 1 mg 25 mg 25 mg 50 mg 50 mg 5 mg 5 mg
Category
Type Inhibitors
Specific against other
Smiles C(F)(F)(F)C1=C(N2C(S1)=NC(CN3N=C(C(F)(F)F)C=C3Cl)=CC2=O)[C@H]4[C@H](C#N)C4
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias GNE0723
Shipping Condition Cool pack
Available
Manufacturer - Targets
iGluR|||NMDAR
Shipping Temperature
Cool pack
Storage Conditions
-20°C
Molecular Weight
467, 78
Description
GNE-0723 is a selective positive allosteric modulator of the NMDA receptor, with an EC50 of 21 nM for GluN2A. It can cross the blood-brain barrier (BBB) and improve outcomes in Dravet syndrome (DS) and Alzheimer's disease (AD).
Pathways
Membrane transporter/Ion channel|||Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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