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B-Raf IN 11

B-Raf IN 11

Item no.	TMO-T19802-200mg
Manufacturer	TargetMol
CASRN	918504-27-5
Amount	200 mg
Quantity options	100 mg 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,9946
Formula	C17H14BrF2N3O3S
Smiles	C(=O)(C=1C=2C(NC1)=NC=C(Br)C2)C3=C(F)C(NS(CCC)(=O)=O)=CC=C3F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Raf
Shipping condition	Cool pack
Available
Manufacturer - Targets	Raf
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	458, 28
Description	B-Raf IN 11 is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.
Bioactivity	N-(3-(5-Bromo-1H-pyrrolo[2, 3-b]pyridine-3-carbonyl)-2, 4-difluorophenyl)propane-1-sulfonamide is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.
Pathways	MAPK

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