Comparison

Dacomitinib hydrate European Partner

Item no. TMO-T19965-500mg
Manufacturer TargetMol
CASRN 1042385-75-0
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Smiles O.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias PF 299804,PF00299804,PF 00299804,PF-299804,PF-00299804,PF299804
Shipping Condition Cool pack
Available
Manufacturer - Targets
EGFR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
487.96
Description
Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and induction of apoptosis in EGFR-expressing tumor cells.
Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close