Comparison

Fimepinostat European Partner

Item no. TMO-T2078-500mg
Manufacturer TargetMol
CASRN 1339928-25-4
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 0,9966
Smiles COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias CUDC-907,PI3K/HDAC Inhibitor,CUDC 907
Shipping Condition Cool pack
Available
Manufacturer - Targets
Apoptosis|||PI3K|||HDAC
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
508.55
Description
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.
Pathways
Apoptosis|||PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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