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Tacrolimus monohydrate

Tacrolimus monohydrate

Item no.	TMO-T20879-500mg
Manufacturer	TargetMol
CASRN	109581-93-3
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O.O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	FK 506,FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Phosphatase\|\|\|Autophagy\|\|\|Antibacterial\|\|\|Antibiotic
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	822.05
Description	Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. It prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro and has strong immunosuppressive activity in vivo.
Pathways	Microbiology/Virology\|\|\|Autophagy\|\|\|Metabolism

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