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PF-9184

PF-9184

Item no.	TMO-T21738-2mg
Manufacturer	TargetMol
CASRN	1221971-47-6
Amount	2 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C21H14Cl2N2O4S
Smiles	OC1=C(NS(=O)(=O)c2ccccc12)C(=O)Nc1ccc(cc1)-c1ccc(Cl)c(Cl)c1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Prostaglandin Receptor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Prostaglandin Receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	461.32
Description	PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 of 16.5 nM, and it inhibits IL-1β-induced PGE2 synthesis in vitro.
Pathways	Immunology/Inflammation\|\|\|GPCR/G Protein
Bioactivity	PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1), IC50 =16.5 nM. PF-9184 inhibits IL-1Î²-induced PGE2 synthesis in vitro.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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