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CID 2745687

CID 2745687

Item no.	TMO-T21874-1mg
Manufacturer	TargetMol
CASRN	264233-05-8
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GPCR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	395.43
Description	CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].
Pathways	GPCR/G Protein\|\|\|Endocrinology/Hormones

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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