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Direct Blue 1

Direct Blue 1

Item no.	TMO-T2194-500mg
Manufacturer	TargetMol
CASRN	2610-05-1
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 1 g 1 mL 200 mg 250 mg 25 mg 2 g 500 mg 5 g 5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	91.79%
Citations	Yu G, et al. Behav Pharmacol. 2013 Dec;24(8):653-8.
Smiles	COc1c(ccc(c1)c1cc(c(cc1)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N)OC)/N=N/c1ccc2c(c1O)c(c(cc2S(=O)(=O)[O-])S(=O)(=O)[O-])N.[Na+].[Na+].[Na+].[Na+]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Pontamine sky blue,Chicago Sky Blue 6B
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GluR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	992.8
Description	Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit Aβ binding.
Pathways	Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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