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Anxiolytic/nonsedative agent-1

Anxiolytic/nonsedative agent-1

Item no.	TMO-T23445-2mg
Manufacturer	TargetMol
CASRN	355022-97-8
Amount	2 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	C(C(N[C@H](C)C1=CC=CC=C1)=O)(=O)C=2C=3C(NC2)=CC=C(N(=O)=O)C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TCS 1205
Shipping condition	Cool pack
Available
Manufacturer - Targets	GABA Receptor
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	337, 33
Target names or alias	TCS 1205
Description	Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for α1β2γ2, α2β2γ2, α5β3γ2, respectively. Anxiolytic/nonsedative agent-1 shows α2 selective efficacy in vitro and anxioselective effects in vivo.
Pathways	Neuroscience\|\|\|Membrane transporter/Ion channel

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