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ON1231320

ON1231320

Item no.	TMO-T23569-500mg
Manufacturer	TargetMol
CASRN	131247-39-8
Amount	500 mg
Quantity options	100 mg 10 mg 1 mL 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg 1 g 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	http://cancerres.aacrjournals.org/content/71/8_Supplement/643
Smiles	C1=CC(F)=CC(F)=C1S(=O)(=O)C1=CC2=CN=C(NC3=CC=C4NC=CC4=C3)N=C2N(C)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	131247-39-8
Available
Molecular Weight	467.45
Bioactivity	ON1231320 is a Polo-like kinase 2 (PLK2) inhibitor. In vitro testing revealed that ON1231320 is a selective inhibitor of PLK2 with no inhibitory activity against PLK1, PLK3, and PLK4. ON1231320 affects cell cycle progression by blocking tumor cells in the G2/M phase however it does not affect normal human fibroblasts.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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