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ABC1183

ABC1183

Item no.	TMO-T23601-5mg
Manufacturer	TargetMol
CASRN	1042735-18-1
Amount	5 mg
Quantity options	100 mg 10 mg 1 mL 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	Cc1ccc(Nc2nc(N)c(s2)C(=O)c2ccc(cc2)C#N)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ABC 1183,ABC-1183
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GSK-3\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	334.39
Description	ABC1183 is a novel diaminothiazole that inhibits GSK3α, GSK3β and CDK9. ABC1183 inhibits the growth of a numerous cancer cell lines by decreasing cell survival by inducing G2/M arrest and through altering GSK3, glycogen synthetase, β-catenin phosphorylation and MCL1 expression, and is orally active.
Pathways	Cell Cycle/Checkpoint\|\|\|PI3K/Akt/mTOR signaling\|\|\|Stem Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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