SL327

Item no.	TMO-T2708-500mg
Manufacturer	TargetMol
CASRN	305350-87-2
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	100.00%
Citations	Valjent E, J Neurosci, 2000, 20(23), 8701-8709.
Smiles	NC(Sc1ccc(N)cc1)=C(C#N)c1ccccc1C(F)(F)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SL 327,SL-327
Shipping Condition	Cool pack
Available
Manufacturer - Targets	DNA/RNA Synthesis\|\|\|MEK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	335.35
Description	SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.
Pathways	MAPK\|\|\|Cell Cycle/Checkpoint\|\|\|DNA Damage/DNA Repair
Bioactivity	SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 uM/0.22 uM; able to transport through the blood-brain barrier.
Receptor	AP-1; MEK1; MEK2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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