« Back
Home /
AKB-6899

AKB-6899

Item no.	TMO-T29797-50mg
Manufacturer	TargetMol
CASRN	1007377-55-0
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	OC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(F)c1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AKB6899
Shipping Condition	Cool pack
Available
Manufacturer - Targets	VEGFR\|\|\|HIF/HIF Prolyl-Hydroxylase\|\|\|HIF
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	290.25
Description	AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth.
Pathways	Metabolism\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis\|\|\|Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T29797-50mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 50 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question