Comparison

GSK-J4 European Partner

Item no. TMO-T3100-200mg
Manufacturer TargetMol
CASRN 1373423-53-0
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Smiles CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias GSK J4
Shipping Condition Cool pack
Available
Manufacturer - Targets
Histone Demethylase|||Apoptosis
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
417.5
Description
GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A (IC50=8.6/6.6 μM). GSK-J4 induces endoplasmic reticulum stress-related apoptosis.
Pathways
Apoptosis|||Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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