Comparison

H-1152 dihydrochloride European Partner

Item no. TMO-T35328-100mg
Manufacturer TargetMol
CASRN 871543-07-6
Amount 100 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Smiles Cl.Cl.C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias H-1152 2HCl,H-1152 dihydrochloride
Shipping Condition Cool pack
Available
Manufacturer - Targets
ROCK
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
392.34
Description
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 values of 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
Pathways
Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Stem Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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