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(S)-PI3Kα-IN-4

(S)-PI3Kα-IN-4

Item no.	TMO-T35488-10mg
Manufacturer	TargetMol
CASRN	2322293-84-3
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C25H23ClFN5O5S
Smiles	CNC(=O)[C@@H](C)Cn1cnc2ccc(cc2c1=O)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2Cl)c1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(S)-PI3Kα-IN-4
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	560
Description	(S)-PI3Kα-IN-4, a potent inhibitor of PI3Kα with an IC50 of 2.3 nM, demonstrates 38.3-, 4.25-, and 4.93-fold selectivity over PI3Kβ, PI3Kδ, and PI3Kγ, respectively, and is suitable for cancer research[1]. (S)-PI3Kα-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution[1].
Pathways	Others
Bioactivity	(S)-PI3KÎ±-IN-4 is a potent inhibitor of PI3KÎ±, with an IC50 of 2.3 nM. (S)-PI3KÎ±-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3KÎ± over PI3KÎ², PI3KÎ´, and PI3KÎ³, respectively. (S)-PI3KÎ±-IN-4 can be used for the research of cancer[1]. (S)-PI3KÎ±-IN-4 (compound 11) is a quinazolin-4(3H)-one derivative with 2-substituted-N-methylpropanamide substitution[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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