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Mn(III)TMPyP

Mn(III)TMPyP

Item no.	TMO-T35966-25mg
Manufacturer	TargetMol
Amount	25 mg
Quantity options	100 mg 10 mg 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	[Cl-].[Cl-].[Cl-].[Cl-].C[n+]1ccc(cc1)C1=C2\C=CC(=N\2)C(c2cc[n+](C)cc2)=c2ccc3=C(C4=N\C(\C=C4)=C(/c4ccc\1n4[Mn](Cl)n23)c1cc[n+](C)cc1)c1cc[n+](C)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	909.013
Description	Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, respectively. Mn(III)TMPyP protected and enhanced the growth of SOD E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 µM.
Pathways	Others

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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