BFH772

Item no.	TMO-T3599-1mL
Manufacturer	TargetMol
CASRN	890128-81-1
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	OCc1cc(Oc2ccc3c(cccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BFH-722
Shipping Condition	Cool pack
Available
Manufacturer - Targets	VEGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	439.39
Description	BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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