Comparison

Lu AE98134 European Partner

Item no. TMO-T36813-10mg
Manufacturer TargetMol
CASRN 849000-18-6
Amount 10 mg
Quantity options 100 mg 10 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 0,98
Formula C21H23N5O3S
Smiles CCCCNS(=O)(=O)c1ccc(OC)c(c1)-c1nnc2c3ccccc3c(C)nn12
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Targets
Others
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
425.5
Description
Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective positive modulator of Nav1.1 channels and also increases the activity of Nav1.2 and Nav1.5 channels while not affecting Nav1.4, Nav1.6, and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].
Pathways
Others
Bioactivity
Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective Nav1.1 channels positive modulator. Lu AE98134 also increases the activity of Nav1.2 and Nav1.5 channels but not of Nav1.4, Nav1.6 and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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