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CX08005

CX08005

Item no.	TMO-T37184-25mg
Manufacturer	TargetMol
CASRN	1256341-22-6
Amount	25 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C28H39N04
Smiles	N(C(=O)C1=C(C(O)=O)C=CC=C1)C2=C(OCCCCCCCCCCCCCC)C=CC=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2-[(2-tetradecoxyphenyl)carbamoyl]benzoic acid
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Phosphatase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	453.61
Description	CX08005 is a protein tyrosine phosphatase 1B inhibitor. CX08005 reduces hepatic lipid accumulation and microcirculatory impairment associated with non-alcoholic fatty liver disease.
Pathways	Metabolism
Bioactivity	Competitive PTP1B inhibitor (IC50 = 0.781 Î¼M). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMA-IR). Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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