Comparison

GGTI-2154 European Partner

Item no. TMO-T37446-10mg
Manufacturer TargetMol
CASRN 251577-10-3
Amount 10 mg
Quantity options 100 mg 10 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 0,98
Formula C24H28N4O3
Smiles C(N[C@@H](CC(C)C)C(O)=O)(=O)C1=C(C=C(NCC2=CN=CN2)C=C1)C3=C(C)C=CC=C3
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Targets
Others
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
420.5
Description
GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against FTase (IC50=5600 nM). Its efficacy and specificity make it a valuable tool for cancer research[1][2].
Pathways
Others
Bioactivity
GGTI-2154 is a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I), with an IC50 of 21 nM. GGTI-2154 shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM). GGTI-2154 can be used for the research of cancer[1][2].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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