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DS44960156

DS44960156

Item no.	TMO-T37655-5mg
Manufacturer	TargetMol
CASRN	2361327-08-2
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Formula	C20H15NO5
Smiles	OC(=O)c1ccc(cc1)C(=O)N1CCc2c(C1)c(=O)oc1ccccc21
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	DHFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	349.34
Description	DS44960156 is a novel selective inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.
Pathways	DNA Damage/DNA Repair\|\|\|Cell Cycle/Checkpoint\|\|\|Metabolism
Bioactivity	DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2; IC50= 1.6 Î¼M).1It is selective for MTHFD2 over MTHFD1 (IC50= >30 Î¼M).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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