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Specnuezhenide

Specnuezhenide

Item no.	TMO-T3803-200mg
Manufacturer	TargetMol
CASRN	39011-92-2
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,9912
Formula	C31H42O17
Smiles	COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Nuezhenide,Nuzhenide
Shipping Condition	Cool pack
Available
Manufacturer - Targets	NF-κB\|\|\|Wnt/beta-catenin
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	686.66
Description	Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling, thereby suppressing IL-1β-induced chondrocyte inflammation. It exerts anti-inflammatory effects in a rat model of osteoarthritis (OA).
Pathways	Cytoskeletal Signaling\|\|\|NF-κB\|\|\|Stem Cells
Bioactivity	Nuezhenide significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect to the seeds of wheat and Chinese cabbage.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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