Comparison

STING Agonist 12b European Partner

Item no. TMO-T38159-1mg
Manufacturer TargetMol
CASRN 2411100-70-2
Amount 1 mg
Quantity options 100 mg 10 mg 1 mg 500 ug 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 0,98
Formula C16H15NO2
Smiles O=C1C=2C(NC=3C1=CC=C(C)C3C)=CC=C(OC)C2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Targets
Others
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
253.3
Description
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
Pathways
Others
Bioactivity
STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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