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Vicenin 2

Vicenin 2

Item no.	TMO-T3851-100mg
Manufacturer	TargetMol
CASRN	23666-13-9
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.37%
Citations	Evaluation of intestinal permeability of vicenin-2 and lychnopholic acid from Lychnophora salicifolia (Brazilian arnicão) using Caco-2 cells. J Nat Prod. 2014 Mar 28;77(3):464-71.
Smiles	OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)c([C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c2oc(cc(=O)c2c1O)-c1ccc(O)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Vicenin -2
Shipping Condition	Cool pack
Available
Manufacturer - Targets	RAAS
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	594.52
Description	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin 2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin 2 could act as a UV light barrier to protect the plants.
Pathways	Endocrinology/Hormones
Bioactivity	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 uM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of alpha-glucosidase, PTP1B, and RLAR. Vicenin -2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin -2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin -2 could act as a UV light barrier to protect the plants.
Receptor	Akt; c-Myc; EGFR; mTOR; p53

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Amount: 100 mg

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