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Opnurasib

Opnurasib

Item no.	TMO-T40292-50mg
Manufacturer	TargetMol
CASRN	2653994-08-0
Amount	50 mg
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1ccc2n(C)ncc2c1)-c1c(Cl)c(C)cc2[nH]ncc12
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NVP-JDQ443,JDQ-443,Opnurasib
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Kras
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	526.03
Description	Opnurasib (JDQ-443) is an orally available and selective and potent covalent KRAS G12C inhibitor with antitumor activity for the study of advanced non-small cell lung cancer.
Pathways	MAPK\|\|\|GPCR/G Protein
Bioactivity	JDQ-443 (example 1a) is a covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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