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AST 487

AST 487

Item no.	TMO-T4053-200mg
Manufacturer	TargetMol
CASRN	630124-46-8
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,9956
Formula	C26H30F3N7O2
Smiles	C(C1=C(C(F)(F)F)C=C(NC(NC2=CC=C(OC=3C=C(NC)N=CN3)C=C2)=O)C=C1)N4CCN(CC)CC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NVP-AST 487
Shipping Condition	Cool pack
Available
Manufacturer - Targets	c-RET\|\|\|FLT\|\|\|VEGFR\|\|\|c-Kit\|\|\|Bcr-Abl
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	529.56
Description	AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.
Pathways	Cytoskeletal Signaling\|\|\|Apoptosis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Bioactivity	AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 mg

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