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OB 24 hydrochloride

OB 24 hydrochloride

Item no.	TMO-T41175-5mg
Manufacturer	TargetMol
CASRN	939825-12-4
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Smiles	Cl.Brc1ccc(CCC2(Cn3ccnc3)OCCO2)cc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Cool pack
Available
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	373, 68
Description	OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferationin vitroand PCA tumor growth and lymph node/lung metastasesin vivo. Synergizes with Taxol.
Pathways	Others

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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