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Hydroxyfasudil

Hydroxyfasudil

Item no.	TMO-T4276L-5mg
Manufacturer	TargetMol
CASRN	105628-72-6
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	Ray P, Wright J, Adam J, Boucharens S, Black D, Brown AR, Epemolu O, Fletcher D, Huggett M, Jones P, Laats S, Lyons A, de Man J, Morphy R, Sherborne B, Sherry L, Straten Nv, Westwood P, York M. Optimisation of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1084-8. doi: 10.1016/j.bmcl.2010.12.104. Epub 2010 Dec 28. PubMed PMID: 21251828.
Smiles	O=c1[nH]ccc2c(cccc12)S(=O)(=O)N1CCCNCC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Hydroxy-Fasudil,HA-1100
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ROCK\|\|\|PKA
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	307.37
Description	Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).
Pathways	Stem Cells\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cell Cycle/Checkpoint\|\|\|Cytoskeletal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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