JK-P3

Item no.	TMO-T4425-100mg
Manufacturer	TargetMol
CASRN	942655-44-9
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	VEGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	323.35
Description	JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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