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cFMS Receptor Inhibitor II European Partner

Item no. TMO-T5586-10mg
Manufacturer TargetMol
CASRN 959860-85-6
Amount 10 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category
Type Inhibitors
Format Powder
Specific against other
Purity 0,9986
Smiles Cc1ccc(Nc2c(cnc3cc(ccc23)-c2ccncc2)C(N)=O)cc1C
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 959860-85-6
Shipping Condition Cool pack
Available
Manufacturer - Targets
c-Fms
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
368.43
Description
cFMS Receptor Inhibitor II is a CSF1R kinase (FMS Receptor; colony stimulating factor 1 receptor; Macrophage colony-stimulating factor receptor) inhibitor with an IC50 of 2.8 nM, demonstrating significant selectivity over other kinases. This compound also exhibits notable CSF1R inhibition with an IC50 of 1.4 μM in cellular assays.
Pathways
Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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