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Dehydrodiisoeugenol

Dehydrodiisoeugenol

Item no.	TMO-T6S1543-2mg
Manufacturer	TargetMol
CASRN	2680-81-1
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,9997
Formula	C20H22O4
Smiles	COc1cc(\C=C\C)cc2C(C)C(Oc12)c1ccc(O)c(OC)c1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	,NF-κB,COX,Antibacterial
Shipping Condition	Cool pack
Available
Manufacturer - Targets	COX\|\|\|NF-κB\|\|\|Antibacterial
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	326.39
Description	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated phosphorylation-dependent proteolysis of inhibitor κB-α and transcriptional activity of NF-κB in the cells.
Pathways	Microbiology/Virology\|\|\|Neuroscience\|\|\|Immunology/Inflammation\|\|\|NF-κB
Bioactivity	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated phosphorylation-dependent proteolysis of inhibitor ÎºB-Î± and transcriptional activity of NF-ÎºB in the cells.

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