IM156

Item no.	TMO-T8532-2mg
Manufacturer	TargetMol
CASRN	1422365-93-2
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	1
Formula	C13H16F3N5O
Smiles	N(C(NC(=N)N1CCCC1)=N)C2=CC=C(OC(F)(F)F)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	OXPHOS
Shipping Condition	Cool pack
Available
Manufacturer - Targets	OXPHOS
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	315.29
Description	IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model [1] [2]. IM156 is a potent oxidative phosphorylation (OXPHOS) inhibitor which is able to be used for the research of solid tumors [3].
Pathways	Apoptosis
Bioactivity	IM156 is an orally bioavailable mitochondrial oxidative phosphorylation (OxPhos) inhibitor, with potential antineoplastic activity.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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