BOT-64

Item no.	TMO-T8705-5mg
Manufacturer	TargetMol
CASRN	113760-29-5
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.08%
Citations	Kim B H , Roh E , Lee H Y , et al. Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-kappaB activation and nuclear factor-kappaB-regulated gene transcription through inactivating inhibitory kappaB kinase beta.[J]. Molecular Pharmacology, 2008, 73(4):1309-1318.
Smiles	CC1(C)Cc2oc(=Nc3ccccc3)sc2C(=O)C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	113760-29-5,IkappaB/IKK
Shipping Condition	Cool pack
Available
Manufacturer - Targets	IκB/IKK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	273.35
Description	BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound
Pathways	NF-κB

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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