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AZD8931 diFuMaric acid

AZD8931 diFuMaric acid

Item no.	TMO-T8751-1mg
Manufacturer	TargetMol
CASRN	1196531-39-1
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.00%
Citations	Zhaomei Mu,Teresa Klinowska,Xiaoshen Dong,et al.AZD8931, an equipotent, reversible inhibitor of signaling by epidermal growth factor receptor (EGFR), HER2, and HER3: preclinical activity in HER2 non-amplified inflammatory breast cancer models.J Exp Clin Cancer Res. 2014 May 30;33(1):47.
Smiles	OC(=O)\C=C\C(O)=O.OC(=O)\C=C\C(O)=O.CNC(=O)CN1CCC(CC1)Oc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1196531-39-1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	706.1
Description	AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).
Pathways	Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling\|\|\|Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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