« Back
Home /
Poziotinib hydrochloride

Poziotinib hydrochloride

Item no.	TMO-T8758-25mg
Manufacturer	TargetMol
CASRN	1429757-68-5
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,9969
Smiles	Cl.COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	HM 781-36B hydrochloride,NOV120101 hydrochloride
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	527.8
Description	Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Pathways	Angiogenesis\|\|\|JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T8758-25mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 25 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question