NSAH

Item no.	TMO-T8800-10mM
Manufacturer	TargetMol
CASRN	1099592-35-4
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.59%
Citations	Tessianna A , Misko, Yi-Ting, et al. Structure-guided design of anti-cancer ribonucleotide reductase inhibitors.[J]. Journal of enzyme inhibition and medicinal chemistry, 2019.
Smiles	Oc1ccccc1C(=O)N\N=C\c1c(O)ccc2ccccc12
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
Shipping Condition	Cool pack
Available
Manufacturer - Targets	DNA/RNA Synthesis
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	306.32
Description	NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.
Pathways	DNA Damage/DNA Repair\|\|\|Cell Cycle/Checkpoint
Bioactivity	NSAH is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 uM and cell-based IC50 of ca.250 nM, respectively.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 1 mL x 10 mM (in DMSO)

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