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IC 86621

IC 86621

Item no.	TMO-T9760-50mg
Manufacturer	TargetMol
CASRN	404009-40-1
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	CC(=O)c1ccc(cc1O)N1CCOCC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	DNA-PK
Shipping Condition	Cool pack
Available
Manufacturer - Targets	DNA-PK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	221.25
Description	IC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 µM for DNA-PK mediated cellular DSB repair.
Pathways	DNA Damage/DNA Repair\|\|\|PI3K/Akt/mTOR signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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