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Arnicolide D

Arnicolide D

Item no.	TMO-TN1405-100mg
Manufacturer	TargetMol
CASRN	34532-68-8
Amount	100 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,9666
Formula	C19H24O5
Smiles	[H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(=O)C(C)=C)[C@]1([H])[C@H](C)C(=O)O2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	mTOR\|\|\|Akt\|\|\|PI3K\|\|\|Caspase\|\|\|STAT
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	332.39
Description	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.
Pathways	Cytoskeletal Signaling\|\|\|Stem Cells\|\|\|Proteases/Proteasome\|\|\|Apoptosis\|\|\|JAK/STAT signaling\|\|\|PI3K/Akt/mTOR signaling
Bioactivity	Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.

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