NI-57

Item no.	TMO-TQ0083-50mg
Manufacturer	TargetMol
CASRN	1883548-89-7
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	100.00%
Citations	Igoe N, et al. Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins. J Med Chem. 2017 Aug 24;60(16):6998-7011.
Smiles	COc1cc(ccc1S(=O)(=O)Nc1ccc2n(C)c(=O)c(C)cc2c1)C#N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1883548-89-7,Epigenetic Reader Domain
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Epigenetic Reader Domain
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	383.42
Description	NI-57 is an inhibitor of the bromodomain and plant homeodomain finger-containing (BRPF) family proteins, with IC50 values of 3.1 nM for BRPF1, 46 nM for BRPF2 (BRD1), and 140 nM for BRPF3.
Pathways	Chromatin/Epigenetic

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