Comparison

Resatorvid European Partner

Item no. TMO-TQ0181-10mM
Manufacturer TargetMol
Amount 1mL*10mM(inDMSO)
Category
Type Inhibitors
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 243984-11-4
Available
purity
100.00%
formula
C15H17ClFNO4S
MolWt
361.82
Pathway
Apoptosis; Immunology/Inflammation
Target
TLR; TNF
Bioactivity
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).
Reference
Ni JQ, et al. Role of toll-like receptor 4 on lupus lung injury and atherosclerosis in LPS-challenge ApoE-/- mice. Clin Dev Immunol. 2013; 2013:476856.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mL*10mM(inDMSO)
Available: In stock
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