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Rat Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

Rat Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

Item no.	IT1-R53Wb-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 500 ug x 2
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Rat (Rattus norvegicus)
Host	CHO cells
Conjugate/Tag	Unconjugated
Purity	90%
Formula	50 mM Tris,150 mM NaCl,pH7.5
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10xHis \| Native, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	113.4 kDa & 83.7 kDa
Manufacturer - Format	Powder
Description	Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Background	Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Molecule	Integrin alpha 3 beta 1
Exp Region	Phe 33 - Glu 992 & Gln 21 - Asp 729
Characteristics	Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA3 and ITGB1, has a calculated MW of 113.4 kDa (ITGA3) & 83.7 kDa (ITGB1). Subunit ITGA3 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 125-150 kDa (ITGA3) and 100-110 kDa (ITGB1) respectively due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 150 mM NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

IT1-R53Wb-100ug-datasheet.pdf

IT1-R53Wb-100ug-safety-datasheet.pdf