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Biotin-COG1410 (TFA)

Biotin-COG1410 (TFA)

Item no.	HY-P2136F-5mg
Manufacturer	MedChem Express
Amount	5 mg
Quantity options	1 mg 5 mg
Category	Other Assays & Kits
Type	Separation, Purification
Specific against	other
Purity	99.25
Citations	[1]Laskowitz DT, et, al. COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury. J Neurotrauma. 2007 Jul;24(7):1093-107. \|[2]Tukhovskaya EA, et, al. COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia. J Neurosci Res. 2009 Feb 15;87(3):677-82. \|[3]Kuai L, et, al. Apolipoprotein E-Mimetic Peptide COG1410 Enhances Retinal Ganglion Cell Survival by Attenuating Inflammation and Apoptosis Following TONI. Front Neurosci. 2019 Sep 13;13:980.
Smiles	CC(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C(C)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C(C)(NC([C@@H](NC([C@@H](NC(C)=O)C)=O)CO)=O)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCCCN)=O)CC(C)C)=O)C)=O)CCCCNC(CCCC[C@@H]1SC[C@]([H])(N2)[C@@]1(NC2=O)[H])=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)C(N)=O)C.OC(C(F)(F)F)=O.[x]
ECLASS 10.1	32170301
ECLASS 11.0	32170301
UNSPSC	41104900
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Apolipoprotein; Apoptosis
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Product Description	Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease[1][2].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P2136F-5mg-safety-datasheet.pdf