Survivin Rabbit pAb (APR22076N)

pAbs-N

Calculated MW: 8kDa/13kDa/15kDa/16kDa/18kDaObserved MW: 16KDa

Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Survivin (NP_001159.2).

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.

Affinity purification